分子夾雑の生命化学

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原著論文 A01班

[すべて]　[A01の成果]　[A02の成果]　[A03の成果]　

    1. R.; Takashima. I.; Uchinomiya. S.; Ojida*. A., Reversible Ratiometric Detection of Highly Reactive Hydropersulfides Using a FRET-Based Dual Emission Fluorescent Probe, Chemical Science, 2017, 8, 1134-1140 DOI: 10.1039/c6sc03856e. 
      Tags: 王子田 A01
    2. J.; Ojida. A.; Hamachi. I., Fluorescence Sensing of Inorganic Phosphate and Pyrophosphate Using Small Molecular Sensors and Their Applications, Topics in Current Chemistry, 2017, 375:30DOI: 10.1007/s41061-017-0120-0 
      Tags: 王子田 A01
    3. N.; Fuchida. H.; Tabata. S.; Uchinomiya. S.; Ojida*. A., Discovery of highly reactive peptide tag by ELISA-type screening for specific cysteine conjugation, Bioorganic & Medicinal Chemistry Letters,2017, 27,3486-3489  DOI: 10.1016/j.bmcl.2017.05.069 
      Tags: 王子田 A01
    4. Delsuc*. N.; Uchinomiya. S.; Ojida. A.; Hamachi. I, A host–guest system based on collagen-like triple-helix hybridization, Chemical Communications, 2017, 53, 6856-6859 DOI :10.1039/C7CC03055J
      Tags:       王子田 A01
    5. H.; Fujisaku. T.; Tanaka. W.; Kubota. R.; Minami. S.; Urayama. K.; Hamachi, I.*, An adaptive supramolecular hydrogel comprising self-sorting double nanofibre networks,Nature Nanotechnology, 2018, 13, 165-175 DOI:10.1038/s41565-017-0026-6 Tags: 浜地 A01
    6. A.; Uchida. N.; Kato. H.; Hisamatsu. R.; Sato, A.; Hagihara. S.; Itami. K.; Torii. K.U., Discovery of Synthetic Small Molecules that Enhance the Number of Stomata: C-H Functionalization Chemistry for Plant Biology, Chem. Commun., 2017, 53, 9632-9635. DOI:10.1039/C7CC04526C Tag: 萩原 A01
    7. K.; Tamura. T.; Hamachi*. I., Recognition-driven chemical labeling of endogenous proteins in multi-molecular crowding live cells, Chemical Communications, Feature Article, 2017, 53, 11972-11983 DOI: 10.1039/c7cc07177a. Tags: 浜地 A01
    8. T.; Song. Z.; Amaike. K.; Lee. S.; Yin. S.; Kiyonaka. S.; Hamachi*. I., Affinity-guided Oxime Chemistry for Selective Protein Acylation in Live Tissue Systems, Journal of the American Chemical Society, 2017, 139(40), 14181-14191 DOI: 10.1021/jacs.7b07339. Tags: 浜地 A01
    9. K.; Nishikawa. Y.; Masuda. M.; Hamachi*. I., Live-cell Protein Sulfonylation Based on Proximity-driven N-Sulfonyl Pyridone Chemistry, Angewandte Chemie International Edition, 2018, 15, 659-662 DOI: 10.1002/anie.201707972. Tags: 浜地 A01
    10. N.; Takahashi. K.; Iwasaki. R.; Yamada. R.; Yoshimura. M.; Endo. T. A. ; Kimura. S.; Zhang, H.; Nomoto. M.; Tada. Y.; Kinoshita. T.; Itami. K.; Hagihara. S.;  Torii. K. U., Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair, Nat. Chem. Biol., 2018, 14, 299-305, DOI: 10.1038/nchembio.2555. Tags: 萩原 A01
    11. M.; Sato. A.; Kuwata. K.; Inukai. Y.; Kinoshita. T.; Itami. K.; Tsuchiya. Y.; Hagihara. S., Discovery of shoot branching regulator targeting strigolactone re-ceptor DWARF14, ACS Central Science, 2018, 4, 230-234. DOI: 10.1021/acscentsci.7b00554 Tags: 萩原A01
    12. Shigemitsu, H.; Fujisaku, T.; Tanaka, W.; Kubota, R.; Minami, S.; Urayama, K.; Hamachi, I.*, An adaptive supramolecular hydrogel comprising self-sorting double nanofibre networks,Nature Nanotechnology, 2018, 13, 165-175 DOI:10.1038/s41565-017-0026-6
      Tags: 浜地 A01
    13. T.; Tamura. T.; Hamachi. I., In situ Construction of Protein-based Semisynthetic Biosensors, ACS Sensors, 2018, 3 ( 3 ) 527 – 539  DOI :10.1021/acssensors.7b00894 Tags: 浜地 A01
    14. S.*; Sakamoto. S.; Wakayama. S.; Morikawa. Y.; Tsujikawa. M.; Hamachi. I.*, Ligand-directed chemistry of AMPA receptors confers live-cell fluorescent biosensors, ACS Chemical Biology,  2018,13 (7), 1880–1889 DOI : 10.1021/acschembio.7b01042 Tags: 浜地 A01
    15. Y.; Uchinomiya. S.; Kobayashi. D.; Endo. M.; Hayashi. T.; Fukuyama. Y.; Hayasaka. H.; Miyasaka. M.; Ueda. T.; Shimada. I.; Hamachi. I., Endogenous Membrane Receptors Labeling by Reactive Cytokines/Growth Factors to Chase Their Dynamics in Live Cells, Chem, 2018, 4, 1451-1464 Doi.org/10.1016/j.chempr.2018.03.021 Tags: 浜地 A01
    16. S.; Masuda. M.; Miki, T.; Hamachi. I.; Sagan. S.; Lequin. O.; Medjoubi. K.; Somogyi. A.; Delsuc*. N.; Policar* C., Graftable SCoMPIs Enable The Labeling and X-Ray Fluorescence Imaging of Proteins, Chemical Science, 2018, 9, 4483-4487 (2018) DOI:10.1039/c8sc00886h Tags: 浜地 A01
    17. T.; Ueda. T.; Goto. T.; Tsukidate. T.; Shapira. Y.; Nishikawa. Y.; Fujisawa. A.; Hamachi*. I., Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide, Nature Communications, 2018, 9, 1870, DOI:10.1038/s41467-018-04343-0 Tags: 浜地 A01
    18. Kubota, R.; Liu, S.; Shigemitsu, H.; Nakamura, K.; Tanaka, W.; Ikeda, M.; Hamachi, I., Imaging-Based Study on Control Factors over Self-Sorting of Supramolecular Nanofibers Formed from Peptide- and Lipid-Type Hydrogelators, Bioconjugate Chemistry, 2018, Jun 20;29(6):2058-2067. DOI:10.1021/acs.bioconjchem.8b00260 Tags: 浜地 A01
    19. G.; Inobe. T.; Amano, T.; Murai. K.; Nukina. N.; Mori. N., N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression, Scientific Reports, 2018, 8, 9585 DOI: 10.1038/s41598-018-27872-6 Tags: 伊野部 A01
    20. T.; Tsukamoto. M.; Nozaki. M., Proteasome-mediated protein degradation is enhanced by fusion ubiquitin with unstructured degron., Biochem. Biophys. Res. Commun., 2018, 501, 948-954 DOI: 10.1016/j.bbrc.2018.05.088 Tags: 伊野部 A01
    21. Yamatsugu, K.; Furuta, M.; Xi, S.; Amamoto, Y.; Liu, J.; Kawashima, S. A.; Kanai, M., Kinetic Analyses and Structure-Activity Relationship Studies of Synthetic Lysine Acetylation Catalysts,  Med. Chem, 2018, Volume 26, Issue 19, 15 , Pages 5359-5367, DOI: 10.1016/j.bmc.2018.07.009 Tags: 山次 A01
    22. S.; Hatano. K.; Tsushima. M.; Nakamura. H., 1-Methyl-4-aryl-urazole (MAUra) Labels Tyrosine in Proximity to Ruthenium Photocatalyst., Chem. Commun. 2018, 54, 5871-5874.  DOI: 10.1016/j.bmc.2018.05.002 Tags: 中村 A01
    23. Ueda, H.; Yoshimori, A.; Nakamura, H., Discovery of bicycle[3,3,1]non-2-ene as a novel skeleton for HIF-1 inhibitors,  Med. Chem, 2018,26(12):3345-3351. DOI: 10.1016/j.bmc.2018.05.002Tags: 中村 A01
    24. R.; Murai. K.; Uchida. N.; Takahashi. K.; Iwasaki. R.; Tada. Y.; Kinoshita. T.; Itami. K.; Torii. U. K.; Hagihara. S., A super strong engineered auxin-TIR1 pair, Plant and Cell Physiology, 2018, 59(8):1538-1544, DOI:10.1093/pcp/pcy127Tags: 萩原 A01
    25. M.; Akhmanova. M.; Merrin. J.; Glanc. M.; Hagihara. S.; Takahashi. K.; Uchida. N.; Torii. U. K.; Friml. J., Rapid and reversible root growth inhibition by TIR1 auxin signalling, Nat. Plants., 2018, 4, 453-459. DOI: 10.1038/s41477-018-0190-1 Tags: 萩原 A01
    26. W. K.;Nishida. Y.;Yamamoto. S.; Ishii. J.; Maruyama. T., Short oligopeptides for biocompatible and biodegradable supramolecular hydrogels. Langmuir, 2018, 34(27), 8065-80742. DOI: 10.1021/acs.langmuir.8b00362 Tags: 丸山 A01
    27. K.; Masada. T.; Kjawano. K.; Futaki. S., Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides. Mol. Pharm., 2018, 15, 1332-1340. DOI: 10.1021/acs.molpharmaceut.7b01130 Tags: 二木A01
    28. Tainaka, K.; Murakami, T.C.; Susaki, E.A.; Shimizu, C.; Saito, R.; Takahashi, K.; Hayashi-Takagi, A.; Sekiya, H.; Arima, Y.; Nojima, S.; Ikemura, M.; Ushiku, T.; Shimizu, Y.; Murakami, M.; Tanaka, K.F.; Iino, M.; Kasai, H.; Sasaoka, T.; Kobayashi, K.; Miyazono, K.; Morii, E.; Isa, T.; Fukayama, M.; Kakita, A.; Ueda, H.R. Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents. Cell Reports, 2018, 24(8), 2196-2210.e9. DOI: 10.1016/j.celrep.2018.07.056. Tags: 田井中A01
    29. H.; Tamura. T.; Hamachi. I., Chemical Proteomics for Subcellular Proteome Analysis, Curr. Opin. Chem. Biol., 2018, 48:1-7, 
      DOI:10.1016/j.cbpa.2018.08.001. 
      Tags: 浜地 A01
    30. R.; Nomura. W.; Iwasaka. T.; Ojima. K.; Kiyonaka. S.; Hamachi. I., A Chemogenetic Approach Using Ni(II) Complex-Agonist Conjugates Allows to Selectively Activate Class A G Protein-Coupled Receptors, ACS Central Science, 2018,4 (9), pp 1211–1221. DOI:10.1021/acscentsci.8b00390 Tags: 浜地 A01
    31. Y.; Imai. H.; Kawaguchi. Y.; Nakase. I.; Kimura. H.; Futaki. S., Modular Redesign of a Cationic Lytic Peptide to Promote the Endosomal Escape of Biomacromolecules, Angew. Chem. Int. Ed. Eng., 57(39), 12771–12774 (2018) 
      DOI: 10.1002/anie.201807534
      Tags:       二木A01
    32. S.; Tsuchima. M.; Nakamura.H., Target-Protein-Selective Inactivation and Labelling Using Oxidative Catalyst. Org. Biomol. Chem. 16, 6168 – 6179 (2018). DOI: 10.1039/C8OB01484A 
      Tags:       中村 A01
    33. Fujisawa, A.; Tamura, T.; Yasueda, Y.; Kuwata, K.; Hamachi, I., Chemical profiling of the endoplasmic reticulum proteome using designer labeling reagents.  Am. Chem Soc. 2018, 140(49), 17060-17070, doi:10.1021/jacs.8b0860
      Tag: 浜地A01
    34. Tamura, T.; Hamachi, I., Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems.  Am. Chem. Soc., 2019, 141(7), 2782–2799, DOI:10.1021/jacs.8b11747
      Tags:       浜地 A01
    35. Sakamoto, S.; Kiyonaka, S.; Hamachi, I., Construction of ligand assay systems by protein-based semisynthetic biosensors.  Opin. Chem. Biol., 2019, 50, 10–18, DOI:10.1016/j.cbpa.2019.02.011
      Tags:       浜地 A01
    36. S.; Hamachi. I., Recent Progress in Chemical Modification of Proteins. Analytical Sciences. Anal. Sci., 2019, 35(1), 5–27, DOI:10.2116/analsci.18R003
      Tags:       浜地 A01
    37. R.; Iguchi. H.; Maruyama. T., Quantification of azide groups on a material surface and a biomolecule using a clickable and cleavable fluorescent compound. RSC Adv. 9, 4621-4625 (2019).  DOI : 10.1039/c8ra09421g
      Tags: 丸山A01
    38. M.; Kitahata. S.; Nishimori. K.; Miyahara. K.; Tokuda. K.; Nishino. T.; Maruyama. T., Surface-functionalization of isotactic polypropylene via dip-coating with a methacrylate-based terpolymer containing perfluoroalkyl groups and poly(ethylene glycol). Polymer J. 51, 489-499 (2019). 
      DOI : 10.1038/s41428-018-0164-1 
      Tags: 丸山A01
    39. Masuda, T.; Baba, K.; Nomura, T.; Tsujita, K.; Murayama, T.; Itoh, T.; Takatani-Nakase, T.; Sokabe, M.; Inagaki, N.; Futaki, S. An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling.  Biol. 2, 243 (2019)
      DOI: 10.1038/s42003-019-0486-3
      Tags: 二木 A01
    40. Hamajima W.; Fujimura A.; Fujiwara Y.; Yamatsugu K.; Kawashima S. A.; Kanai M., Site-Selective Synthetic Acylation of a Target Protein in Living Cells Promoted by a Chemical Catalyst/Donor System, ACS Chem. Biol., 2019, 14(6), 1102-1109.
      DOI: 10.1021/acschembio.9b00102
      Tags: 山次 A01
    41. Ito K.; Tatsumi T.; Takahashi K.; Shimizu Y.; Yamatsugu K.; Kanai M., A Stable and Cleavable O-Linked Spacer for Drug Delivery Systems,  Pharm. Bull., 2020,68 (3),212-215
      DOI: https://doi.org/10.1248/cpb.c19-00376
      Tags: 山次 A01
    42. T.; Anzai. H.; Nemoto. N., Selection of Peptides that Associate with Dye-Conjugated Solid Surfaces in a pH-Dependent Manner Using cDNA Display. ACS Omega, 2019, 4, 7378-7384. DOI: 10.1021/acsomega.9b00631
      Tags: 寺井 A01
    43. Anzai, H.; Terai, T.; Jayathilake, C.; Suzuki, T.; Nemoto, N., A novel immuno-PCR method using cDNA display.  Biochem.,2019,578, 1-6. DOI: 10.1016/j.ab.2019.04.017
      Tags: 寺井 A01
    44. S.; Yoshida. M.; Hatano. K.; Matsumura. M.; Nakamura. H., N’-Acyl-N-methylphenylenediamine as a Novel Proximity Labeling Agent for Signal Amplification in Immunohistochemisty. Bioorg. Med. Chem., 27(6), 1110-1118 (2019) DOI:10.1016/j.bmc.2019.01.036. 
      Tags:       中村 A01
    45. S.; Sato. S.;Asami. H.; Hasegawa. T.; Kohno. J.; Nakamura. H., Design of S-S Bond Containing Maleimide-conjugated closo-Dodecaborate (SSMID): Identification of Unique Modification Sites on Albumin and Investigation of Intracellular Uptake. Org. Biomol. Chem. 17, 5496–5499 (2019) DOI: 10.1039/C9OB00584F.
      Tags:       中村 A01
    46. Y.; Katsuragi. K.; Sato. A.; Yoshimori. A.; Tanuma. S.; Nakamura. H., Structure-based drug design of novel carborane-containing nicotinamide phosphoribosyltransferase inhibitors. Bioorg. Med. Chem. 27(13),2832-2844 (2019). DOI:10.1016/j.bmc.2019.05.013.
      Tags: 中村 A01
    47. Kubota, R.; Kiyonaka, S.; Hamachi, I. On-cell coordination chemistry: Chemogenetic activation of membrane-bound glutamate receptors in living cells. Methods in Enzymology, 2019, 622, 411-430,　DOI: 10.1016/bs.mie.2019.02.033
      Tags:       浜地 A01
    48. Sakamoto, S.; Yamaura, K.;  Numata, T.; Harada, F.; Amaike, K.; Inoue, R.; Kiyonaka, S.; Hamachi, I., Construction of a Fluorescent Screening System of Allosteric Modulators for the GABAA Receptor Using a Turn-On Probe. ACS Central Sci., 2019, 5(9), 1541-1553, DOI:10.1021/acscentsci.9b00539
      Tags: 浜地 A01
    49. Ueda, T.; Tamura, T,; Hamachi, I. Development of a cell-based ligand-screening system for identifying Hsp90 inhibitors. Biochemistry, 2020, 59, 2, 179-182 doi:10.1021/acs.biochem.9b00781
      Tags: 浜地 A01
    50. C.; Terai. T.;Nemoto. N., cDNA Display Mediated Immuno-PCR (cD-IPCR): A Novel PCR-based Antigen Detection Method
      Bio-protocol,2019, 9, e3457  DOI: 10.21769/BioProtoc.3457
      Tags: 寺井 A01
    51. C.; Kumachi. S.; Arai. H.; Motohashi. M.; Terai. T.; Murakami. A.; Nemoto. N, In vitro selection of anti-gliadin single-domain antibodies from a naïve library for cDNA-display mediated immuno-PCR
      Anal. Biochem.,2020,589, 113490  DOI: 10.1016/j.ab.2019.113490
      Tags: 寺井 A01
    52. Y.; Komatsu. T.; Kyo. E.; Matsuzaki. H.; Hata. K.; Watanabe. T.; Ueno. T.;  Hanaoka. K.; Urano. Y.,
      Separation-Based Enzymomics Assay for the Discovery of Altered Peptide-Metabolizing Enzymatic Activities in Biosamples
      Anal. Chem., 2019, 91, 11497-11501 doi:10.1021/acs.analchem.9b03016
      Tags: 小松A01
    53. Toru Komatsu, and Yasuteru Urano
      Chemical Toolbox for “Live” Biochemistry to Understand Enzymatic Functions in Living Systems,  Biochem., 2020, 167 (2), 139–149
      doi:10.1093/jb/mvz074
      Tags:       小松A01
    54. Ogihara S.; Komatsu. T.; Itoh Y.; Miyake. Y.; Suzuki. T.; Yanagi. K.; Kimura. Y.; Ueno. T.: Hanaoka. K.; Kojima H.: Okabe. T.; Nagano. T.; Urano. Y., Metabolic Pathway-oriented Screening Targeting S-Adenosyl-L-methionine Reveals the Epigenetic Remodeling Activities of Naturally Occurring Catechols
      Am. Chem. Soc., 2020, 142, 1, 21-26 DOI :10.1021/jacs.9b08698
      Tags: 小松A01
    55. N.; Fuchida. H.; Sato. M.; Watari K.; Shibata. T.; Kuwata. K.; Miura. C.; Okamoto. K.; Hatsuyama. Y.; Tokunaga. K.;Sakamoto. S.; Morimoto. S.; Abe. Y.; Shiroishi. M.; Caaveiro. M. M. J.; Ueda. T.; Tamura. T.; Matsunaga. N.; Nakao. T.; Koyanagi. S.; Ohdo. S.; Yamaguchi. Y.; Hamachi. I.; Ono. M.; Ojida. A., Selective and reversible modification of kinase cysteines with chlorofluoroacetamides, Nature Chemical Biology,volume 15, 250–258(2019)
      DOI:10.1038/s41589-018-0204-3
      Tags:       王子田A01

    56. S.; Jevtic. M.; Kurashige. N.; Fuchida. H.; Kido. M.; Tani. K.; Zenmyo. N.; Uchinomiya. S.; Harada. H.; Itakura. M.; Hamachi. I.; Shigemoto. R.; Ojida. A., Electron Microscopic Detection of Single Membrane Proteins by a Specific Chemical Labeling, iScience, 22, 256-268 (2019).
      DOI : 10.1016/j.isci.2019.11.025
      Tags: 王子田A01
    57. K.; Shibata. T.; Fujita. H.; Shinoda. A.; Murakami. Y.; Abe. H.; Kawahara. A.; Ito. H.; Akiba. J.; Yoshida. S.; Kuwano. M.; Ono. M.;, NDRG1 activates VEGF-A-induced angiogenesis through PLCγ1/ERK signaling in mouse vascular endothelial cells, Communications Biologyvolume 3, Article number: 107 (2020)
      DOI:https://doi.org/10.1038/s42003-020-0829-0
      Tags:       小野A01
    58. S.; Nakamura. H.;, Protein Chemical Labeling Using Biomimetic Radical Chemistry, Molecules 24(21), 3980 (2019)
      DOI: 10.3390/molecules24213980
      Tags:       中村A01
    59. S.; Yoshida. M.; Hatano. K.; Matsumura. M.; Nakamura. H.;, N’-Acyl-N-methylphenylenediamine as a Novel Proximity Labeling Agent for Signal Amplification in Immunohistochemisty, Bioorg. Med. Chem.27(6), 1110-1118 (2019) 
      DOI: 10.1016/j.bmc.2019.01.036
      Tags:       中村A01
    60. Y.; Katsuragi. K.; Sato. A.; Yoshimori. A.; Tanuma. S.; Nakamura. H.;, Structure-based drug design of novel carborane-containing nicotinamide phosphoribosyltransferase inhibitors, Bioorg. Med. Chem. 27(13), 2832-2844 (2019).
      DOI:10.1016/j.bmc.2019.05.013
      Tags:       中村A01
    61. M.; Sato. S.; Niwa. T.; Taguchi. H.; Nakamura. H.;, Catalyst-Proximity Protein Chemical Labelling on Affinity Beads Targeting Endogenous Lectins, Chem. Commun. 55, 13275-13278 (2019). 
      DOI: 10.1039/C9CC05231C
      Tags:       中村A01
    62. S.; Sato. S.; Asami. H.; Hsegawa. T.; Kohno. J.; Nakamura. H.;, Design of S-S Bond Containing Maleimide-conjugated closo-Dodecaborate (SSMID): Identification of Unique Modification Sites on Albumin and Investigation of Intracellular Uptake, Org. Biomol. Chem.17(22), 5496–5499(2019)
      Tags:       中村A01
    63. M.; Asatyas. S.; Sato. S.; Nakagawa. F.; Hayashi. T.; Nakamura. H.;, Distribution and Concentration of Small Molecules in Single Cells Visualized by νB-H Raman Microscopy, RSC Advance. 9, 23973–23978(2019) 
      DOI: 10.1039/c9ra04228h
      Tags:       中村A01
    64. 佐藤伸一; 對馬理彦; 中村浩之;, タンパク質ケミカルラベリングにおける一電子移動反応の活用Utilization of Single Electron Transfer Reaction in Protein, 有機合成化学協会誌77(5) 463-471 (2019) 
      DOI: 10.5059/yukigoseikyokaishi.77.463
      Tags:       中村A01
    65. T; Liu. H.; Ozeki. Y.; Sato. S.; Hayashi. T.; Nakamura. H.;, Imaging of Cellular Uptake of Boron Cluster Compound by Stimulated Raman Scattering Microscopy, Applied Physics Express12(11), 112004 (2019)
      DOI: 10.7567/1882-0786/ab4a5d
      Tags:       中村A01
    66. S.; Matsumura. M.; Kadonosono. T.; Abe. S.; Ueno. T.; Ueda. H.; Nakamura. H.;, Site-Selective Protein Chemical Modification in Exposed Tyrosine Residues Using Tyrosine Click Reaction, Bioconjugate Chem.31, 1417−1424 (2020) 
      DOI: 10.1021/acs.bioconjchem.0c00120
      Tags:       中村A01
    67. S.; Nakane. K.; Nakamura. H.;, Laccase-Catalysed Tyrosine Click Reaction, Org. Biomol. Chem. 18, 3664-3668 (2020)
      DOI: 10.1039/d0ob00650e.
      Tags:       中村A01
    68. T.; Fuse. S.; Nakamura. H.;, Novel Photochemical Conversion of Isoxazoles to 5-Hydroxyimidazolines: Possible Protein Labeling at Lysine Residues, Org. Lett. 22, 3460-3463 (2020)
      DOI: 10.1021/acs.orglett.0c00910
      Tags:       中村A01
    69. M.; Saito. R.; Kakita. A.; Tainaka. K., Rapid Chemical Clearing of White Matter in the Post-Mortem Human Brain by 1,2-hexanediol Delipidation, Bioorg. Med. Chem. Lett. 29(15), 1886-1890 (2019) DOI: 10.1016/j.bmcl.2019.05.049 Tags: 田井中A01
    70. E.A.; Shimizu. C.; Kuno. A.; Tainaka. K.; Li. X.; Nishi. K.; Morishima. K.; Ono. H.; Ode. K.L.; Saeki. Y.; Miyamichi. K.; Isa. K.; Yokoyama. C.; Kitaura. H.; Ikemura. M.; Ushiku. T.; Shimizu. Y.; Saito. T.; Saido. T.C.; Fukayama. M.; Onoe. H.; Touhara. K.; Isa. T.; Kakita. A.; Shibayama. M.; Ueda. H.R., Versatile whole-organ/body staining and imaging based on electrolyte-gel properties of biological tissues, Nat. Commun.11(1), 1982 (2020) DOI: 10.1038/s41467-020-15906-5. Tags: 田井中A01
    71. N.; Tainaka. K.; Macpherson. T.; Hikida. T.; Yamaguchi. S.; Sasaoka. T., Neurotransmission Through Dopamine D1 Receptors Is Required for Aversive Memory Formation and Arc Activation in the Cerebral Cortex, Neurosci. Res.(2020) 156, 58-65
      DOI: 10.1016/j.neures.2020.04.006. Tags: 田井中A01
    72. Hatanaka, W.; Takeuchi, H.; Koga, M.; Ryujin, T.; Kishimura, A.; Katayama, Y.; Tsukiji, S.; Mori, T., Synthesis of transmembrane molecules by click chemistry, Chemistry Letters, 2019, 48, 433– DOI: 10.1246/cl.190009
      Tags:       築地A01
    73. Nakamura, A.; Katahira, R.; Sawada, S.; Shinoda, E.; Kuwata, K.; Yoshii, T.; Tsukiji, S., Chemogenetic control of protein anchoring to endomembranes in living cells with lipid-tethered small molecules, Biochemistry, 2020, 59, 205– DOI: 10.1021/acs.biochem.9b00807.
      Tags:       築地A01
    74. Sumito, N.; Koeda, S.; Umezawa, N.; Inoue, Y.; Tsukiji, S.; Higuchi, T.; Mizuno, T., Development of cell-penetration PG-surfactants and its application in external peptide delivery to cytosol, Bioconjugate Chemistry, 2020, 31, 821– DOI: 10.1021/acs.bioconjchem.9b00877.
      Tags:       築地A01
    75. Nakamura, A.; Oki, C.; Kato, K.; Fujinuma, S.; Maryu, G.; Kuwata, K.; Yoshii, T.; Matsuda, M.; Aoki, K.; Tsukiji, S., Engineering orthogonal, plasma membrane-specific SLIPT systems for multiplexed chemical control of signaling pathways in living single cells, ACS Chemical Biology, 2020, 15, 1004– DOI: 10.1021/acschembio.0c00024.
      Tags:       築地A01
    76. Nakamura, A.; Oki, C.; Sawada, S.; Yoshii, T.; Kuwata, K.; Rudd, A. K.; Devaraj, N. K.; Noma, K.; Tsukiji, S., Designer palmitoylation motif-based self-localizing ligand for sustained control of protein localization in living cells and Caenorhabditis elegans, ACS Chemical Biology, 2020, 15, 837– DOI: 10.1021/acschembio.0c00014.
      Tags:       築地A01
    77. Takaoka, Y.; Miyagawa, S.; Nakamura, A.; Egoshi, S.; Tsukiji, S.; Ueda, M., Hoechst-tagged fluorescein diacetate for the fluorescence imaging-based assessment of stomatal dynamics in Arabidopsis thaliana, Scientific Reports, 2020, 10, 5333. DOI: https://doi.org/10.1038/s41598-020-62239-w.
      Tags: 築地A01
    78. Suzuki, S.; Ikuta, M.; Yoshii, T.; Nakamura, A.; Kuwata, K.; Tsukiji, S., Golgi recruitment assay for visualizing small-molecule ligand–target engagement in cells, Chemical Communications, Advance Article. DOI: 1039/d0cc02020f.
      Tags:       築地A01
    79. Tamura, T.; Takato, M.; Shiono, K.; Hamachi, I. Development of a Photoactivatable Proximity Labeling Method for the Identification of Nuclear Proteins. Chemistry Letters, 2020, 49, 145-148 doi:10.1246/cl.190804
      Tags: 浜地 A01
    80. Kubota, R.; Nakamura, K.; Torigoe, S.; Hamachi, I. The Power of Confocal Laser Scanning Microscopy in Supramolecular Chemistry: In situ Real‐time Imaging of Stimuli‐Responsive Multicomponent Supramolecular Hydrogels., ChemistryOPEN, 2020, 9, 67-79 doi:10.1002/open.201900328
      Tags:       浜地 A01
    81. R.; Makuta. M.; Suzuki. R.; Ichikawa. M.; Tanaka. M.; Hamachi. I., Force generation by a propagating wave of supramolecular nano fibers, Nature Communications, 2020, 11:3541.
      Tags: 浜地A01
    82. H.; Kubota. R.; Nakamura. K.; Matsuzaki. T.; Minami. S.; Aoyama. T.; Urayama. K.; Hamachi. I., Protein-Responsive Protein-Release of Supramolecular/polymer Hydrogel Composite Integrating Enzyme Activation SystemsNature Communications, 2020, 11:3859.
      Tags: 浜地 A01
    83. Kubota, R.; Nagao, K., Tanaka, W.; Matumura, R.; Aoyama, T.; Urayama, K.; Hamachi, I., Control of seed formation allows two distinct self-sorting patterns of supramolecular nano fibers. Nature Communications, 2020, 11(1), 4100. doi:10.1038/s41467-020-17984-x.  
      Tags: 浜地 A01
    84. Zhu, H.; Tamura, T.; Fujisawa, A.; Nishikawa, Y.; Cheng, R.; Takato, M.; Hamachi, I., Imaging and profiling of proteins under oxidative conditions in cells and tissues by hydrogen-peroxide-responsive labeling.  Am. Chem. Soc., 2020, 142(37), 15711–15721. doi:10.1021/jacs.0c02547.
      Tags:       浜地 A01
    85. Tamura, T.; Fujisawa, A.; Tsuchiya, M.; Shen, Y.; Nagao, K.; Kawano, S.; Tamura, Y.; Endo, T.; Umeda, M.; Hamachi, I., Organelle membrane-specific chemical labeling and dynamic imaging in living cells. Nature Chem.Biol., 2020, 6(12), 1361-1367. doi:10.1038/s41589-020-0
      Tags: 浜地 A01
    86. Kubota, R.; Torigoe, S.; Liu, S.; Hamachi, I., In Situ Real-time Confocal Imaging of a Self-assembling Peptide-grafted Polymer Showing pH-responsive Hydrogelation.  Lett., 2020, 49(11), 1319-1323. doi:10.1246/cl.200513
      Tags: 浜地 A01
    87. Shiraiwa, K.; Cheng, R.; Nonaka, H.; Tamura, T.; Hamachi, I., Chemical Tools for Endogenous Protein Labeling and Profiling, Cell Chemical Biology, 2020, 27(8), 970-985(2020) doi:10.1016/j.chem
      Tags: 浜地 A01
    88. Zhu, H.; Hamachi, I., Fluorescence imaging of drug target proteins using chemical probes. Journal of Pharmaceutical Analysis, 2020, 10(5), 426-433. jpha.2020.05.013
      Tags: 浜地 A01
    89. S.; Nakane. K.; Nakamura. H.; Laccase-Catalysed Tyrosine Click Reaction, Org. Biomol. Chem.18, 3664-3668 (2020) DOI: 10.1039/d0ob00650e.
      Tags: 中村A01
    90. M.; Sato. S.; Nakane. K.; Nakamura. H.; Target protein identification on the photocatalyst-functionalized magnetic affinity beads, Current Protocol.101(1) DOI:10.1002/cpps.108
      Tags: 中村A01
    91. S.; Nakamura. H.; Labeling of Peroxidase-Induced Oxidative Stress Hotspots by Hemin-Catalyzed Tyrosine Click, Chem. Pharm. Bull.68(9), 885-890 (2020) DOI:10.1248/cpb.c20-00434
      Tags: 中村A01
    92. Y.; Yoshimori. A.; Bajorath. J.; Nakamura. H.; Prediction of an MMP-1 Inhibitor Activity Cliff Using the SAR Matrix Approach and Its Experimental Validation, Sci. Rep. 10, 14710 (2020) DOI:10.1038/s41598-020-71696-2
      Tags: 中村A01
    93. T.; Sato. S.; Niwa. T.; Taguchi. H.; Nakamura. H.; Oyoshi. T.; G-Quadruplex-Proximity Protein Labeling Based on Peroxidase Activity, Chem. Commun. 2020, 56, 11641-11644 DOI:10.1039/D0CC02571B 
      Tags: 中村A01
    94. S.; Morita. T.; Nakamura. H.;, Rhodium(III)-Catalyzed Direct C-H Functionalization of Isoxazoles with Alkynes, Alkenes and Sulfoxonium Ylides, Org. Biomol. Chem. 18, 8625–8628 (2020) DOI:10.1039/D0OB02027C
      Tags:       中村A01
    95. K.; Takeda. S.; Yunoki. A.; Tsuchii. T.; Tanaka. T.; Maruyama. T., Preparation of affinity membranes using polymer phase separation and azido-containing surfactants. Colloids Surf A Physicochem Eng Asp, 2020, DOI: 10.1016/j.colsurfa.2020.125802
      Tags: 丸山A01
    96. W. K.; Yamamoto. Y.; Nishida. S.; Ienaga. H.; Aoi. T.; Maruyama. T., Hydrogel formation by short D-peptide for cell-culture scaffolds. Mater. Sci. Eng. C, 2020, 111, 110746. DOI:10.1016/j.msec.2020.110746
      Tags: 丸山A01
    97. K.; Hara. M.; Nishino. T.; Maruyama. T., One-step biotinylation of cellulose paper by polymer-coating to prepare a paper-based analytical device.Anal. Chem., 2020, 92, 1978−1987. DOI: 10.1021/acs.analchem.9b04373
      Tags:       丸山A01
    98. T.; Manabe. Y.; Ito. K.; Chang. T-C.; Kabayama. K.; Ohshima. S.; Kametani. Y.; Miur. A.; Furukawa. H.; Inaba. H.; Matsuura. K.; Fukase. K., Immunological Evaluation of Co‐assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants as Self‐adjuvanting Anti‐breast Cancer Vaccine Candidates.Angew. Chem. Int. Ed.2020, 59, 17705-17711. DOI: 10.1002/anie.202007999. Tags: 真鍋A01
    99. R.E.; Di Carluccio. C.; Guzmán-Caldentey. J.; Gaglione. R.; Battista. F.; Chiodo. F.; Manabe. Y.; Arciello. A.; Del Vecchio. P.; Fukase. K.; Molinaro. A.; Martín-Santamaría. S.; Crocker. P.R.; Marchetti. R.; Silipo. A., Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10.iScience2020, 23, 101231. DOI: 10.1016/j.isci.2020.101231. Tags: 真鍋A01
    100. K.; Ono. R.; Manabe. Y.; Masui. S.; Atomi. H.; Fukase. K., Total Syntheses of C60- and C100-Dolichols. J. Org. Chem.2020, 85, 11549-11559. DOI: 10.1021/acs.joc.0c01327. Tags: 真鍋A01
    101. K.; Manabe. Y.; Ichikawa. H.; Miyake. S.; Tsutsui. M.; Kabayama. K.; Yamaji. T.; Tanaka. K.; Hung. S.-C.; Fukase. K., Concise and Reliable Syntheses of Glycodendrimers via Self-Activating Click Chemistry: A Robust Strategy for Mimicking Multivalent Glycan–Pathogen Interactions. J. Org. Chem.2020, 85, 16014-16023. DOI: 10.1021/acs.joc.0c01547. Tags: 真鍋A01
    102. M.; Yoshihara. K.; Suda. K.; Nakaoka. H.; Yachida. N.; Ueda. H.; Sugino. K.; Mori. Y.; Yamawaki. K.; Tamura. R.; Ishiguro. T.; Motoyama. T.; Watanabe. Y.; Okuda. S.; Tainaka. K.; Enomoto. T., Three-dimensional understanding of the morphological complexity of the human uterine endometrium. iScience24(4):102258 (2021). doi: 10.1016/j.isci.2021.102258. Tags: 田井中A01
    103. S.I.; Takahashi. K.; Mano. T.; Matsumoto. K.; Katsumata. T.; Shi. S.; Tainaka. K.; Ueda. H.R.; Ehata. S.; Miyazono. K., Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing. Commun. Biol.4(1):294 (2021) doi: 10.1038/s42003-021-01786-y. Tags: 田井中A01
    104. S.; Nishimura. K.; Morita. K.; Kanemitsu. S.; Nishida. Y.; Morimoto. T.; Aoi. T.; Tamura. A.; Maruyama. T., Microenvironment pH-induced selective cell death for potential cancer therapy using nanofibrous self-assembly of a peptide amphiphile, Biomacromolecules, 2021, 22(6), 2524-2531
      DOI: 10.1021/acs.biomac.1c00267
      Tags: 丸山 A01
    105. M.;  Kaneko. K.; Hara. M.; Matsui. M.; Morita. K.; Maruyama. T., Covalent immobilization of gold nanoparticles on a plastic substrate and subsequent immobilization of biomolecules, RSC Adv., 2021, 11, 23409-23417.
      DOI: 10.1039/D1RA03902D
      Tags: 丸山 A01
    106. M.; Sato. S.; Nakane.K.; Nakamura. H., Target protein identification on the photocatalyst-functionalized magnetic affinity beads, Current Protocol. 101(1) DOI: 10.1002/cpps.108
      Tags: 中村 A01
    107. S.; Nakamura. H., Labeling of Peroxidase-Induced Oxidative Stress Hotspots by Hemin-Catalyzed Tyrosine Click Chem. Pharm. Bull. 68(9), 885-890 (2020). DOI:10.1248/cpb.c20-00434.
      Tags: 中村 A01
    108. Y.; Yoshimori. A.; Bajorath. J.; Nakamura. H., Prediction of an MMP-1 Inhibitor Activity Cliff Using the SAR Matrix Approach and Its Experimental Validation, Sci. Rep. 10, 14710 (2020). DOI:10.1038/s41598-020-71696-2
      Tags: 中村 A01
    109. K.; Sato. S.; Niwa. T.; Tsushima. M.; Tomoshige. S.; Taguchi. H.; Ishikawa. M.; Nakamura. H., Proximity Histidine Labeling by Umpolung Strategy Using Singlet Oxygen, J. Am. Chem. Soc. 143, 20, 7726–7731(2021) doi: 10.1021/jacs.1c01626  
      Tags:       中村 A01
    110. T.; Tahara. K.; Suzuki. S.; Hatano. Y.; Kuwata. K.; Tsukiji. S., An improved intracellular synthetic lipidation-induced plasma membrane anchoring system for SNAP-tag fusion proteins, Biochemistry, 2020, 59, 3044–3050. DOI: 10.1021/acs.biochem.0c00410.
      Tags:       築地A01
    111. S.; Nakamura,.A.; Yoshii. T.; Kuwata. K.; Nakatsu. F.; Tsukiji. S., Protein-recruiting synthetic molecules targeting the Golgi surface, Chemical Communications, 2020, 56, 15422–15425. DOI: 10.1039/D0CC06908F.
      Tags:       築地A01
    112. H.; Yoshii. T.; Kawasaki. S.; Hayashi. K.; Tsutsui. K.; Oki. C.; Tsukiji. S.; Saito. H., Light-controllable RNA-protein devices for translational regulation of synthetic mRNAs in mammalian cells, Cell Chemical Biology, 2021, 28, 662–674. DOI: 10.1016/j.chembiol.2021.01.002.
      Tags:       築地A01
    113. M.; Yoshii. T.; Ikuta. M.; Tsukiji. S., Synthetic protein condensates that inducible recruit and release protein activity in living cells, Journal of the American Chemical Society, 2021, 143, 6434–6446. DOI: 10.1021/jacs.0c12375.
      Tags:       築地A01
    114. Sato, M. Matsumura, H. Ueda, H. Nakamura,
      Preparation of an antigen-responsive fluorogenic immunosensor by tyrosine chemical modification of the antibody complementarity determining region ChemComm, 57, 9760-9763 (2021). DOI: 10.1039/d1cc03231c
      Tags: 中村 A01
    115. Asawa, K. Nishida, K. Domae, K. Kawai, H. S. Ban, H. Asami, J.-Y. Kohno, S. Okada, H. Tokuma, D. Sakano, S. Kume, M. Tanaka, H. Nakamura,
      Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation,
      Bioconjugate Chem. 32(11),2377–2385. DOI: 10.1021/acs.bioconjchem.1c00431
      Tags:       中村 A01
    116. Y.; Hatsuzawa. S.; Yoshimori. A.; Yamada. K.; Katoh. A.; Kouji. H.; Nakamura. H., Comprehensive exploration of chemical space using trisubstituted carboranes, Sci. Rep., 2021,11,24101 DOI: 10.1038/s41598-021-03459-6 Tags: 中村 A01
    117. Ojima, K.; Shiraiwa, K.; Doura, T.; Takato, M.; Komatsu, K.; Yuzaki, M.; Hamachi, I.; Kiyonaka, S. Ligand-directed two-step labeling to quantify neuronal glutamate receptor trafficking. Nature Communications, 2021, 12, 831. doi:10.1038/s41467-021-21082-x
      Tags: 浜地 A01
    118. Thimaradka, V.; Oh, J. H.; Heroven, C.; Aricescu, A. R.; Yuzaki, M.; Tamura, M.; Hamachi, I. Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent.  Med. Chem., 2021, 30, 115947. doi:10.1016/j.bmc.2020.115947
      Tags: 浜地 A01
    119. Ueda, T.; Tamura, T.; Kawano, M.; Shiono, K.; Hobor, F.; Wilson, A. J.; Hamachi, I. Enhanced Suppression of a Protein?Protein Interaction in Cells Using Small-Molecule Covalent Inhibitors Based on an N-Acyl-N-alkyl Sulfonamide Warhead  Am. Chem. Soc., 2021, 143, 4766–4774. doi:10.1021/jacs.1c00703
      Tags:       浜地  A01
    120. Nakamura, K.; Tanaka, W.; Sada, K.; Kubota, R.; Aoyama, T.; Urayama, K.; Hamachi, I. Photo-triggered spatially controlled out-of-equilibrium patterns of peptide nanofibers in a self-sorting double network hydrogel.  Am. Chem. Soc., 2021, 143, 19532–19541.doi:10.1021/jacs.1c09172
      Tags:       浜地 A01
    121. Mino, T.; Sakamoto, S.; Hamachi, I. Recent applications of N-acyl imidazole chemistry in chemical biology.  Biotechnol. Biochem., 2021, 85, 53–60. doi:10.1093/bbb/zbaa026
      Tags:       浜地 A01
    122. Tsuchiya, M.; Tamura, T.; Hamachi, I. Organelle-selective labeling of choline-containing phospholipids(CPLs) and real-time imaging in living cells. Current Protocols, 2021, 1, e105. doi:10.1002/cpz1.105
      Tags: 浜地 A01
    123. Kubota, R.; Tanaka, W.; Hamachi, I. Microscopic Imaging Techniques for Molecular Assemblies: Electron, Atomic Force, and Confocal Microscopies.  Rev., 2021, 121, 14281–14347. doi.org/10.1021/acs.chemrev.0c01334
      Tags:       浜地 A01
    124. Tsutsui, M.; Manabe, Y.; Kabayama, K.; Fukase, K. Synthesis of ABO blood group antigens and functional glycan display on the cell surface. Arkivoc, 2021, iv, 168-185.DOI: 10.24820/ark.5550190.p011.362
      Tags: 真鍋A01
    125. Carluccio, D. C., Forgione, R. E.; Montefiori, M.; Civera, M.; Sattin, S.; Smaldone, G.; Fukase, K.; Manabe, Y.; Crocker, P. R.; Molinaro, A.; Marchetti, R.; Silipo, A. Behavior of glycolylated sialoglycans in the binding pockets of murine and human CD22. iScience, 2021, 24, 101998. DOI: 10.1016/j.isci.2020.101998
      Tags: 真鍋A01
    126. Kaneda-Nakashima, K.; Zhang, Z.; Manabe, Y.; Shimoyama, A.; Kabayama, K.; Watabe, T.; Kanai, Y.; Ooe, K.; Toyoshima, A.; Shirakami, Y.; Yoshimura, T.; Fukuda, M.; Hatazawa, J.; Nakano, T.; Fukase, K.; Shinohara, A. a-Emitting cancer therapy using 211At‐AAMT targeting LAT1. Cancer Sci., 2021, 112, 1132-1140. DOI: 10.1111/cas.14761
      Tags:       真鍋A01
    127. Shirakawa, A.; Manabe, Y.; Fukase, K.; Recent advances in the chemical biology of N-glycans. Molecules, 2021, 26, 1040. DOI: 10.3390/molecules26041040
      Tags: 真鍋A01
    128. Manabe, Y. Chemical biology study on N-glycans. Trends in Glycosci. Glycotechnol.2021, 33, E63-E67. DOI: 10.4052/tigg.2109.2E
      Tags: 真鍋A01
    129. Shirakawa, A.; Manabe, Y.; Marchetti, R.; Yano, K.; Masui, S.; Silipo, A.; Molinaro, A.; Fukase, K. Chemical Synthesis of Sialyl N-Glycans and Analysis of Their Recognition by Neuraminidase.  Chem. Int. Ed.2021, 60, 24686-24693. DOI: 10.1002/anie.202111035
      Tags: 真鍋A01
    130. Carluccio, C.; Forgione, R. E.; Bosso, A.; Yokoyama, S.; Manabe, Y.; Pizzo, E.; Molinaro, A.; Fukase, K.; Fragai, M.; Bensing, B. A.; Marchetti, R.*; Silipo A.* Molecular recognition of sialoglycans by streptococcal Siglec-like adhesins: toward the shape of specific inhibitors. RSC Chem. Biol.2021, 2, 1618-1630. DOI: 10.1039/d1cb00173f
      Tags: 真鍋A01
    131. Tsuchii, K. Kaneko, K. Morita, T. Nishino, T. Maruyama, A rewritable surface on a plastic substrate using fluorous affinity, ACS Appl. Mater. Interfaces, 2022. DOI: 10.1021/acsami.1c18633
      Tags: 丸山 A01
    132. Tsushima, S. Sato, K. Miura, T. Niwa, H. Taguchi, H. Nakamura
      Intracellular Photocatalytic-Proximity Labeling for Profiling Protein–Protein Interactions in Microenvironments, ChemComm. accepted (2022). DOI: 10.1039/D1CC05764B
      Tags:       中村 A01
    133. T.; Oki. C.; Watahiki. R.; Nakamura. A.; Tahara. K.; Kuwata. K.; Furuta. T.; Tsukiji. S., Chemo-optogenetic protein translocation system using a photoactivatable self-localizing ligand, ACS Chemical Biology, 2021, 16, 1557–1565. DOI: 10.1021/acschembio.1c00416.
      Tags:       築地A01
    134. M.; Tsukiji. S., Modularly built synthetic membraneless organelles enabling targeted protein sequestration and release, Biochemistry, 2021, 60, 3273–3276. DOI: 10.1021/acs.biochem.1c00675.
      Tags:       築地A01
    135. Kono, M.; Kakegawa, W.; Yoshida, K.; Yuzaki, M., Interneuronal NMDA receptors regulate long-term depression and motor learning in the cerebellum, J Physiol (London), 2019, 597, 3, 903-920.
      DOI: 10.1113/JP276794
      Tags: 掛川A01
    136. Matsuda, S.; Kakegawa, W.; Yuzaki, M., PhotonSABER: new tool shedding light on endocytosis and learning mechanisms in vivo, Communicative & Integrative Biology, 2019, 12, 1, 34-37.
      DOI: 10.1080/19420889.2019.1586048
      Tags: 掛川A01
    137. Kakegawa, W.; Katoh, A.; Narumi, S.; Miura, E.; Motohashi, J.; Takahashi, A.; Kohda, K.; Fukazawa, Y.; Yuzaki, M.; Matsuda, S., Optogenetic control of synaptic AMPA receptor endocytosis reveals roles of LTD in motor learning, Neuron, 2018, 99, 985-998.
      Tags: 掛川A01
    138. Kawano K, Yokoyama F, Kamasaka K, Kawamoto J, Ogawa T, Kurihara T, Futaki S. Design of the N-Terminus Substituted Curvature-Sensing Peptides That Exhibit Highly Sensitive Detection Ability of Bacterial Extracellular Vesicles. Chem. Pharm. Bull. (Tokyo). 2021, 69(11):1075-1082. DOI: 10.1248/cpb.c21-00516. 
      Tags: 二木A01
    139. Sakamoto K, Furukawa H, Arafiles JVV, Imanishi M, Matsuura K, Futaki S. Artificial Nanocage Formed via Self-Assembly of β-Annulus Peptide for Delivering Biofunctional Proteins into Cell Interiors. Bioconjug. Chem. 2022, 33(2):311-320. DOI: 10.1021/acs.bioconjchem.1c00534. 
      Tags:       二木A01
    140. Shinga K, Iwata T, Murata K, Daitoku Y, Michibata J, Arafiles JVV, Sakamoto K, Akishiba M, Takatani-Nakase T, Mizuno S, Sugiyama F, Imanishi M, Futaki S. L17ER4: A cell-permeable attenuated cationic amphiphilic lytic peptide. Bioorg. Med. Chem. 2022, 61:116728. DOI: 10.1016/j.bmc.2022.116728. 
      Tags: 二木A01
    141. Y. Utomo, S. Okada, A. Sumiyoshi, I. Aoki, H. Nakamura
      Development of an MRI contrast agent for both detection and inhibition of the amyloid-β fibrillation process
      RSC Adv. 12, 5027-5030 (2022) DOI: 10.1039/D2RA00614F      　　　　　　　　　　　　　　　　　　　　　　　　　Tags: 中村 A01
    142. Sakai T, Kawano K, Iino M, Takeuchi T, Imanishi M, Futaki S. Loosening of Lipid Packing by Cell-Surface Recruitment of Amphiphilic Peptides by Coiled-Coil Tethering. Chembiochem. 2019, 20(16):2151-2159. doi: 10.1002/cbic.201900347.
      Tags: 二木A01
    143. Kawano K, Ogushi M, Masuda T, Futaki S. Development of a Membrane Curvature-Sensing Peptide Based on a Structure-Activity Correlation Study. Chem Pharm Bull (Tokyo). 2019, 67(10):1131-1138. doi: 10.1248/cpb.c19-00465. 
      Tags: 二木A01
    144. Hsu WY, Masuda T, Afonin S, Sakai T, Arafiles JVV, Kawano K, Hirose H, Imanishi M, Ulrich AS, Futaki S. Enhancing the activity of membrane remodeling epsin-peptide by trimerization. Bioorg Med Chem Lett. 2020, 30(12):127190. doi: 10.1016/j.bmcl.2020.127190. 
      Tags: 二木A01
    145. Masuda T, Hirose H, Baba K, Walrant A, Sagan S, Inagaki N, Fujimoto T, Futaki S. An Artificial Amphiphilic Peptide Promotes Endocytic Uptake by Inducing Membrane Curvature. Bioconjug Chem. 2020, 31(6):1611-1615. doi: 10.1021/acs.bioconjchem.0c00239. 
      Tags: 二木A01
    146. Kuroki K, Sakai T, Masuda T, Kawano K, Futaki S. Membrane anchoring of a curvature-inducing peptide, EpN18, promotes membrane translocation of octaarginine. Bioorg Med Chem Lett. 2021, 43:128103. doi: 10.1016/j.bmcl.2021.128103. 
      Tags: 二木A01
    147. Kawano K, Yokoyama F, Kawamoto J, Ogawa T, Kurihara T, Futaki S. Development of a Simple and Rapid Method for In Situ Vesicle Detection in Cultured Media. J Mol Biol. 2020, 432(22):5876-5888. doi: 10.1016/j.jmb.2020.09.009. 
      Tags: 二木A01
    148. Sakamoto K, Michibata J, Hirai Y, Ide A, Ikitoh A, Takatani-Nakase T, Futaki S. Potentiating the Membrane Interaction of an Attenuated Cationic Amphiphilic Lytic Peptide for Intracellular Protein Delivery by Anchoring with Pyrene Moiety. Bioconjug Chem. 2021, 32(5):950-957. doi: 10.1021/acs.bioconjchem.1c00101. 
      Tags: 二木A01
    149. Iwata T, Hirose H, Sakamoto K, Hirai Y, Arafiles JVV, Akishiba M, Imanishi M, Futaki S. Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides. Angew Chem Int Ed Engl. 2021, 60(36):19804-19812. doi: 10.1002/anie.202105527.
      Tags: 二木A01
    150. Futaki S. Design and Creation of Functional Membrane-Interacting Peptides.  Org. Chem. Jpn, 2020, 78(11): 1013–1020. DOI: 10.5059/yukigoseikyokaishi.78.1058
      Tags:       二木A01
    151. Kentarou Sakamoto, Hiroto Furukawa, Jan Vincent V. Arafiles, Miki Imanishi, Kazunori Matsuura,* Shiroh Futaki*

    Artificial nanocage formed via self-assembly of β-annulus peptide for delivering biofunctional proteins into cell interiors. Bioconjugate Chemistry, 2022, 33, 311-320. DOI: 10.1021/acs.bioconjchem.1c00534

    Tags: 松浦A02、二木A01

    1. Noda, N.; Ozawa, T.;, Castanospermine suppresses CD44 ectodomain cleavage as revealed by transmembrane bioluminescent sensors.  Cell Sci., 135, jcs259314 (2022).
      Doi: 10.1242/jcs.259314.
      Tags: 小澤A01
    2. Nishiguchi, T.; Yoshimura, H.; Kasai, R.S.; Fujiwara, T.K.; Ozawa T.;, Synergetic roles of Formyl Peptide Receptor 1 oligomerization in ligand-induced signal transduction. ACS Chem. Biol., 18, 2577-2587 (2020). 
      Doi: 10.1021/acschembio.0c00631.
      Tags: 小澤A01
    3. Kondo, T.; Iwatani, Y.; Matsuoka, K.; Fujino, T.; Umemoto, S.; Yokomaku, Y.; Ishizaki, K.; Kito, S.; Sezaki, T.; Hayashi, G.; Murakami, H. Antibody-like proteins that capture and neutralize SARS-CoV-2, Science Advances 2020 6, eabd3916. doi: 10.1126/sciadv.abd3916.
      Tags: 林A01
    4. Ogata, M.; Hayashi, G.; Ichiu, A.; Okamoto, A. L-DNA-tagged fluorescence in situ hybridization for highly sensitive imaging of RNAs in single cells, Organic and Biomolecular Chemistry 2020 18, 8084-8088. doi: 10.1039/d0ob01635g.
      Tags: 林A01
    5. Hao, F.; Murphy, K. J.; Kujirai, T.; Kamo, N.; Kato, J.; Koyama, M.; Okamoto, A.; Hayashi, G.; Kurumizaka, H.; Hayes, J. J. Acetylation-modulated communication between the H3 N-terminal tail domain and the intrinsically disordered H1 C-terminal domain, Nucleic Acids Research 2020 48, 11510-11520. doi: 10.1093/nar/gkaa949.
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    6. Kondo, T.; Eguchi, M.; Kito, S.; Fujino, T.; Hayashi, G.; Murakami, H. cDNA TRAP display for rapid and stable in vitro selection of antibody-like proteins, Chemical Communications 2021 57, 2416-2419. doi: 10.1039/d0cc07541h.
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    7. Kamo, N.; Kujirai, T.; Kurumizaka, H.; Murakami, H.; Hayashi, G.* (co-corresponding author); Okamoto, A.* Organoruthenium-Catalyzed Chemical Protein Synthesis to Elucidate the Functions of Epigenetic Modifications on Heterochromatin Factors, Chemical Science 2021 12, 5926-5937. doi: 10.1039/d1sc00731a.
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    8. Kamo, N.; Hayashi, G.* (co-corresponding author); Okamoto, A.* Silyl-protected propargyl glycine for multiple labeling of peptides by chemoselective silyl-deprotection, Tetrahedron Letters 2021 73, 153093. doi: 10.1016/j.tetlet.2021.153093.
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    9. Kondo, T.; Eguchi, M.; Tsuzuki, N.; Murata, N.; Fujino, T.; Hayashi, G.; Murakami, H. Construction of a Highly Diverse mRNA Library for In Vitro Selection of Monobodies, bio-protocols 2021 11, e4125. doi: 10.21769/BioProtoc.4125
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    10. Koyama, K.; Hayashi, G.; Ueda, H.; Ota, S.; Nagae, G.; Aburatani, H.; Okamoto, A. Base-Resolution Analysis of 5-hydroxymethylcytidine by Selective Oxidation and Reverse Transcription Arrest, Organic and Biomolecular Chemistry 2021 19, 6478-6486. doi: 10.1039/d1ob00995h.
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    11. Kondo, T.; Matsuoka, K.; Umemoto, S.; Fujino, T.; Hayashi, G.; Iwatani, Y.; Murakami, H. Monobodies with potent neutralizing activity against SARS-CoV-2 Delta and other variants of concern, Life Science Alliance 2022 5, e202101322. doi: 10.26508/lsa.202101322.
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    12. Senoo, A; Yamada, Y.; Ojima, K.; Doura, T.; Hamachi, I.; Kiyonaka S. Orthogonal activation of metabotropic glutamate receptor using coordination chemogenetics. Frontiers in Chemistry, 2022, 9, 825669. doi:10.3389/fchem.2021.825669
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    13. Futaki S. Functional Peptides That Target Biomembranes: Design and Modes of Action. Chem Pharm Bull (Tokyo). 2021;69(7):601-607. doi: 10.1248/cpb.c21-00140. PMID: 34193708.
      Tags: 二木A01
    14. Nagano Y, Arafiles JVV, Kuwata K, Kawaguchi Y, Imanishi M, Hirose H, Futaki S. Grafting Hydrophobic Amino Acids Critical for Inhibition of Protein-Protein Interactions on a Cell-Penetrating Peptide Scaffold. Mol Pharm. 2021 Dec 27. doi: 10.1021/acs.molpharmaceut.1c00671. Epub ahead of print. PMID: 34958576.
      Tags: 二木A01

    15. Kusano, S.; Nakamura, S.; Izumi, M.; Hagihara, S. Development of 1,8-naphthalimide dyes for rapid imaging of subcellular compartments in plants. Chem Commun (Camb)DOI:10.1039/d1cc05798g
      Tags: 萩原 A01
    16. Yoshimura, M.; Kim, FS.; Takise, R.; Kusano, S.; Nakamura, S.; Izumi, M.; Yagi, A.; Itami, K.; Hagihara　 Development of potent inhibitors for strigolactone receptor DWARF 14. Chem. Commun., 2020, 56, 14917-14919
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    17.  Shohei Uchinomiya, Naoya Matsunaga, Koichiro Kamoda, Ryosuke Kawagoe, Akito Tsuruta, Shigehiro Ohdo, Akio Ojida, Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells, Commun, 56, 3023 – 3026 (2020)
      DOI: 10.1039/C9CC09993J
      Tags: 王子田　A01
    18. Mami Sato, Hirokazu Fuchida, Naoya Shindo, Keiko Kuwata, Keisuke Tokunaga, Guo Xiao-Lin, Ryo Inamori, Keitaro Hosokawa, Kosuke Watari, Tomohiro Shibata, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo, Mayumi Ono, Akio Ojida, Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines, ACS Medicinal Chemistry Letters, 11, 1137-1144 (2020).
      DOI:10.1021/acsmedchemlett.9b00574
      Tags: 王子田　A01
    19.  Nattha Yongwattana, Nutsara Mekjinda, Wannee Thepsing, Supasara Ounsuk, Pravit Wongkongkatep, Tulyapruek Tawonsawatruk, Itaru Hamachi, Akio Ojida, Jirarut Wongkongkatep, Fluorescence Determination of Soluble Pyrophosphate Levels in Synovial Fluid as a Marker of Pseudogout Using Middle Point of Quantification Concept and Molecular Sensor,ScienceAsia, 46S, 36-42 (2020).
      DOI:10.2306/scienceasia1513-1874.2020.S005

      Tags: 王子田　A01

    20.  Noriaki Nakamura, Shohei Uchinomiya, Kazuya Inoue, Akio Ojida, Trimethyl-Substituted Carbamate as a Versatile Self-Immolative Linker for Fluorescence Detection of Enzyme Reactions,Molecules, 25, 2153 (2020).
      DOI:10.3390/molecules25092153.
      Tags: 王子田　A01
    21. Chizuru Miura, Naoya Shindo, Kei Okamoto, Tomoyo Osawa, Akio Ojida, Fragment-Based Discovery of Irreversible Covalent Inhibitors of Cysteine Proteases Using Chlorofluoro acetamide Library,  Pharm. Bull., 68(11), 1074-1081(2020).
      DOI: 10.1248/cpb.c20-00547
      Tags: 王子田　A01
    22. Keisuke Tokunaga, Mami Sato, Keiko Kuwata, Chizuru Miura, Hirokazu Fuchida, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo, Naoya Shindo, and Akio Ojida, Bicyclobutane Carboxylic Amide as a Cysteine-Directed Strained Electrophile for Selective Targeting of Proteins,  Am. Chem. Soc., 142, 43, 18522–18531 (2020).
      DOI: 10.1021/jacs.0c07490
      Tags: 王子田　A01
    23.  Anna Kanegae,Yusuke Takata, Ippei Takashima, Shohei Uchinomiya, Ryosuke Kawagoe, Kazuteru Usui, Akira Yamashita, Jirarut Wongkongkatep, Manabu Sugimoto, Akio Ojida , A multicolor and ratiometric fluorescent sensing platform for metal ions based on arene–metal-ion contact,Communications chemistry, 4:104 (2021).
      DOI: 10.1038/s42004-021-00541-y
      Tags: 王子田　A01
    24. Daiki Yamane, Satsuki Onitsuka, Suyong Re, Hikaru Isogai, Rui Hamada, Tadanari Hiramoto, Eiji Kawanishi, Kenji Mizuguchi, Naoya Shindo, Akio Ojida, Selective covalent targeting of SARS-CoV-2 main protease by enantiopure chlorofluoroacetamide, Chemical Science, 13, 3027-3034 (2022), DOI:1039/D1SC06596C
      Tags: 王子田　A01
      DOI: 10.1039/D1SC06596C

     

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